Astros Roster & Staff
Transactions
| Date | Transaction |
| 05/19/26 | Houston Astros placed RHP Lance McCullers Jr. on the 15-day injured list retroactive to May 16, 2026. Right shoulder inflammation. |
| 05/19/26 | Houston Astros activated RHP Nate Pearson from the 15-day injured list. |
| 05/19/26 | Houston Astros sent CF Taylor Trammell on a rehab assignment to Corpus Christi Hooks. |
| 05/19/26 | Houston Astros activated CF Jake Meyers from the 10-day injured list. |
| 05/19/26 | Houston Astros sent CF Taylor Trammell on a rehab assignment to Corpus Christi Hooks. |
| 05/19/26 | Houston Astros optioned 3B Shay Whitcomb to Sugar Land Space Cowboys. |
| 05/18/26 | Houston Astros activated SS Jeremy Peña from the 10-day injured list. |
| 05/18/26 | Houston Astros placed 2B Jose Altuve on the 10-day injured list retroactive to May 17, 2026. Left oblique strain. |
| 05/18/26 | Houston Astros designated RHP Cody Bolton for assignment. |
| 05/18/26 | Houston Astros recalled RHP Jason Alexander from Sugar Land Space Cowboys. |
| 05/12/26 | Houston Astros sent CF Jake Meyers on a rehab assignment to Corpus Christi Hooks. |
| 05/12/26 | Houston Astros sent SS Jeremy Peña on a rehab assignment to Corpus Christi Hooks. |
| 05/12/26 | Houston Astros activated RHP Tatsuya Imai from the 15-day injured list. |
| 05/12/26 | Houston Astros sent SS Jeremy Peña on a rehab assignment to Corpus Christi Hooks. |
| 05/12/26 | Houston Astros sent LHP Josh Hader on a rehab assignment to Corpus Christi Hooks. |
| 05/12/26 | Houston Astros sent CF Jake Meyers on a rehab assignment to Corpus Christi Hooks. |
| 05/12/26 | Houston Astros optioned RHP Logan VanWey to Sugar Land Space Cowboys. |
| 05/09/26 | Houston Astros placed LHP Bennett Sousa on the 15-day injured list retroactive to May 6, 2026. Left elbow inflammation. |
| 05/09/26 | Houston Astros transferred RHP Hunter Brown from the 15-day injured list to the 60-day injured list. Right shoulder strain. |
| 05/09/26 | Houston Astros claimed LF Rhylan Thomas off waivers from Seattle Mariners. |
| 05/09/26 | Houston Astros optioned LF Rhylan Thomas to Sugar Land Space Cowboys. |
| 05/09/26 | Houston Astros recalled RHP Jayden Murray from Sugar Land Space Cowboys. |
| 05/08/26 | Houston Astros selected the contract of RHP Logan VanWey from Sugar Land Space Cowboys. |
| 05/08/26 | Houston Astros sent LF Dustin Harris outright to Sugar Land Space Cowboys. |
| 05/07/26 | Houston Astros signed free agent CF Daniel Johnson to a minor league contract. |
| 05/07/26 | Houston Astros optioned RHP Jason Alexander to Sugar Land Space Cowboys. |
| 05/06/26 | Houston Astros placed SS Carlos Correa on the 10-day injured list retroactive to May 5, 2026. Left ankle tendon injury. |
| 05/06/26 | Houston Astros sent CF Daniel Johnson outright to Sugar Land Space Cowboys. |
| 05/06/26 | Houston Astros recalled 3B Shay Whitcomb from Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros sent LHP Josh Hader on a rehab assignment to Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros sent RHP Nate Pearson on a rehab assignment to Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros sent LHP Josh Hader on a rehab assignment to Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros sent RHP Nate Pearson on a rehab assignment to Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros sent RHP Tatsuya Imai on a rehab assignment to Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros activated SS Nick Allen from the 10-day injured list. |
| 05/05/26 | Houston Astros sent RHP Tatsuya Imai on a rehab assignment to Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros designated LF Dustin Harris for assignment. |
| 05/05/26 | Houston Astros placed C Yainer Diaz on the 10-day injured list. Left oblique strain. |
| 05/05/26 | Houston Astros recalled RHP Jason Alexander from Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros recalled LF Zach Dezenzo from Sugar Land Space Cowboys. |
| 05/05/26 | Houston Astros optioned RHP Ryan Weiss to Sugar Land Space Cowboys. |
| 05/04/26 | Houston Astros activated LF Zach Cole. |
| 05/04/26 | Houston Astros designated CF Daniel Johnson for assignment. |
| 05/04/26 | Houston Astros activated LF Zach Dezenzo from the 10-day injured list. |
| 05/04/26 | Houston Astros optioned 3B Shay Whitcomb to Sugar Land Space Cowboys. |
| 05/04/26 | Houston Astros recalled CF Zach Cole from Sugar Land Space Cowboys. |
| 05/04/26 | Houston Astros selected the contract of C César Salazar from Sugar Land Space Cowboys. |
| 05/04/26 | Houston Astros optioned LF Zach Dezenzo to Sugar Land Space Cowboys. |
| 05/03/26 | Houston Astros activated RHP Ryan Weiss from the paternity list. |
| 05/03/26 | Houston Astros optioned RHP Jayden Murray to Sugar Land Space Cowboys. |
| 05/01/26 | Houston Astros sent SS Nick Allen on a rehab assignment to Corpus Christi Hooks. |
| 05/01/26 | Houston Astros optioned RHP Jason Alexander to Sugar Land Space Cowboys. |